WEE1 inhibition sensitizes osteosarcoma to radiotherapy

BACKGROUND: The use of radiotherapy in osteosarcoma (OS) is controversial due to its radioresistance. OS patients currently treated with radiotherapy generally are inoperable, have painful skeletal metastases, refuse surgery or have undergone an intralesional resection of the primary tumor. After ir...

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Detalles Bibliográficos
Autores principales: PosthumaDeBoer, Jantine, Würdinger, Thomas, Graat, Harm CA, van Beusechem, Victor W, Helder, Marco N, van Royen, Barend J, Kaspers, Gertjan JL
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103478/
https://www.ncbi.nlm.nih.gov/pubmed/21529352
http://dx.doi.org/10.1186/1471-2407-11-156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103478/
https://www.ncbi.nlm.nih.gov/pubmed/21529352
http://dx.doi.org/10.1186/1471-2407-11-156

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