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WEE1 inhibition sensitizes osteosarcoma to radiotherapy
BACKGROUND: The use of radiotherapy in osteosarcoma (OS) is controversial due to its radioresistance. OS patients currently treated with radiotherapy generally are inoperable, have painful skeletal metastases, refuse surgery or have undergone an intralesional resection of the primary tumor. After ir...
Autores principales: | PosthumaDeBoer, Jantine, Würdinger, Thomas, Graat, Harm CA, van Beusechem, Victor W, Helder, Marco N, van Royen, Barend J, Kaspers, Gertjan JL |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103478/ https://www.ncbi.nlm.nih.gov/pubmed/21529352 http://dx.doi.org/10.1186/1471-2407-11-156 |
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