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A Multiwell Platform for Studying Stiffness-Dependent Cell Biology

Adherent cells are typically cultured on rigid substrates that are orders of magnitude stiffer than their tissue of origin. Here, we describe a method to rapidly fabricate 96 and 384 well platforms for routine screening of cells in tissue-relevant stiffness contexts. Briefly, polyacrylamide (PA) hyd...

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Detalles Bibliográficos
Autores principales: Mih, Justin D., Sharif, Asma S., Liu, Fei, Marinkovic, Aleksandar, Symer, Matthew M., Tschumperlin, Daniel J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103526/
https://www.ncbi.nlm.nih.gov/pubmed/21637769
http://dx.doi.org/10.1371/journal.pone.0019929