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Detailed Analysis of Variants in FTO in Association with Body Composition in a Cohort of 70-Year-Olds Suggests a Weakened Effect among Elderly

BACKGROUND: The rs9939609 single-nucleotide polymorphism (SNP) in the fat mass and obesity (FTO) gene has previously been associated with higher BMI levels in children and young adults. In contrast, this association was not found in elderly men. BMI is a measure of overweight in relation to the indi...

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Detalles Bibliográficos
Autores principales: Jacobsson, Josefin A., Almén, Markus Sällman, Benedict, Christian, Hedberg, Lilia A., Michaëlsson, Karl, Brooks, Samantha, Kullberg, Joel, Axelsson, Tomas, Johansson, Lars, Ahlström, Håkan, Fredriksson, Robert, Lind, Lars, Schiöth, Helgi B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103532/
https://www.ncbi.nlm.nih.gov/pubmed/21637715
http://dx.doi.org/10.1371/journal.pone.0020158