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Genetic regulation of parasite infection: empirical evidence of the functional significance of an IL4 gene SNP on nematode infections in wild primates

BACKGROUND: Susceptibility to parasite infection affects fitness-related processes, such as mate choice and survival, yet its genetic regulation remains poorly understood. Interleukin-4 (IL4) plays a central role in the humoral immune defence against nematode parasite infections, inducing IgE switch...

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Detalles Bibliográficos
Autores principales: Clough, Dagmar, Kappeler, Peter M, Walter, Lutz
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104205/
https://www.ncbi.nlm.nih.gov/pubmed/21501512
http://dx.doi.org/10.1186/1742-9994-8-9