Expression of mutant alpha-synuclein modulates microglial phenotype in vitro

BACKGROUND: Increased reactive microglia are a histological characteristic of Parkinson's disease (PD) brains, positively correlating with levels of deposited α-synuclein protein. This suggests that microglial-mediated inflammatory events may contribute to disease pathophysiology. Mutations in...

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Detalles Bibliográficos
Autores principales: Rojanathammanee, Lalida, Murphy, Eric J, Combs, Colin K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104357/
https://www.ncbi.nlm.nih.gov/pubmed/21554732
http://dx.doi.org/10.1186/1742-2094-8-44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104357/
https://www.ncbi.nlm.nih.gov/pubmed/21554732
http://dx.doi.org/10.1186/1742-2094-8-44

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