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Expression of mutant alpha-synuclein modulates microglial phenotype in vitro
BACKGROUND: Increased reactive microglia are a histological characteristic of Parkinson's disease (PD) brains, positively correlating with levels of deposited α-synuclein protein. This suggests that microglial-mediated inflammatory events may contribute to disease pathophysiology. Mutations in...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104357/ https://www.ncbi.nlm.nih.gov/pubmed/21554732 http://dx.doi.org/10.1186/1742-2094-8-44 |