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Lack of Association between the Tlr4 (Lps(d)/Lps(d)) Genotype and Increased Susceptibility to Escherichia coli Bladder Infections in Female C3H/HeJ Mice
Toll-like receptor 4 is thought to have a primary role in host defense against Escherichia coli bladder colonization, based on mouse models of urinary tract infection using C3H/HeJ female mice. This strain carries a point mutation in the Tlr4 gene, which renders the mice unresponsive to lipopolysacc...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104495/ https://www.ncbi.nlm.nih.gov/pubmed/21628500 http://dx.doi.org/10.1128/mBio.00094-11 |