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Lack of Association between the Tlr4 (Lps(d)/Lps(d)) Genotype and Increased Susceptibility to Escherichia coli Bladder Infections in Female C3H/HeJ Mice

Toll-like receptor 4 is thought to have a primary role in host defense against Escherichia coli bladder colonization, based on mouse models of urinary tract infection using C3H/HeJ female mice. This strain carries a point mutation in the Tlr4 gene, which renders the mice unresponsive to lipopolysacc...

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Detalles Bibliográficos
Autores principales: Suhs, Kaleigh A., Marthaler, Brodie R., Welch, Rodney A., Hopkins, Walter J.
Formato: Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104495/
https://www.ncbi.nlm.nih.gov/pubmed/21628500
http://dx.doi.org/10.1128/mBio.00094-11