Recombinant Trimeric HA Protein Immunogenicity of H5N1 Avian Influenza Viruses and Their Combined Use with Inactivated or Adenovirus Vaccines

BACKGROUND: The highly pathogenic avian influenza (HPAI) H5N1 virus continues to cause disease in poultry and humans. The hemagglutinin (HA) envelope protein is the primary target for subunit vaccine development. METHODOLOGY/PRINCIPAL FINDINGS: We used baculovirus-insect cell expression to obtain tr...

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Detalles Bibliográficos
Autores principales: Lin, Shih-Chang, Huang, Ming-Hsi, Tsou, Pei-Chun, Huang, Li-Min, Chong, Pele, Wu, Suh-Chin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104987/
https://www.ncbi.nlm.nih.gov/pubmed/21655326
http://dx.doi.org/10.1371/journal.pone.0020052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104987/
https://www.ncbi.nlm.nih.gov/pubmed/21655326
http://dx.doi.org/10.1371/journal.pone.0020052

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