Design, Synthesis, and Characterization of a Highly Effective Hog1 Inhibitor: A Powerful Tool for Analyzing MAP Kinase Signaling in Yeast

The Saccharomyces cerevisiae High-Osmolarity Glycerol (HOG) pathway is a conserved mitogen-activated protein kinase (MAPK) signal transduction system that often serves as a model to analyze systems level properties of MAPK signaling. Hog1, the MAPK of the HOG-pathway, can be activated by various env...

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Detalles Bibliográficos
Autores principales: Dinér, Peter, Veide Vilg, Jenny, Kjellén, Jimmy, Migdal, Iwona, Andersson, Terese, Gebbia, Marinella, Giaever, Guri, Nislow, Corey, Hohmann, Stefan, Wysocki, Robert, Tamás, Markus J., Grøtli, Morten
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104989/
https://www.ncbi.nlm.nih.gov/pubmed/21655328
http://dx.doi.org/10.1371/journal.pone.0020012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104989/
https://www.ncbi.nlm.nih.gov/pubmed/21655328
http://dx.doi.org/10.1371/journal.pone.0020012

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