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Design, Synthesis, and Characterization of a Highly Effective Hog1 Inhibitor: A Powerful Tool for Analyzing MAP Kinase Signaling in Yeast
The Saccharomyces cerevisiae High-Osmolarity Glycerol (HOG) pathway is a conserved mitogen-activated protein kinase (MAPK) signal transduction system that often serves as a model to analyze systems level properties of MAPK signaling. Hog1, the MAPK of the HOG-pathway, can be activated by various env...
Autores principales: | Dinér, Peter, Veide Vilg, Jenny, Kjellén, Jimmy, Migdal, Iwona, Andersson, Terese, Gebbia, Marinella, Giaever, Guri, Nislow, Corey, Hohmann, Stefan, Wysocki, Robert, Tamás, Markus J., Grøtli, Morten |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104989/ https://www.ncbi.nlm.nih.gov/pubmed/21655328 http://dx.doi.org/10.1371/journal.pone.0020012 |
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