Inflammation Triggers Emergency Granulopoiesis through a Density-Dependent Feedback Mechanism

Normally, neutrophil pools are maintained by homeostatic mechanisms that require the transcription factor C/EBPα. Inflammation, however, induces neutrophilia through a distinct pathway of “emergency” granulopoiesis that is dependent on C/EBPβ. Here, we show in mice that alum triggers emergency granu...

Descripción completa

Detalles Bibliográficos
Autores principales: Cain, Derek W., Snowden, Pilar B., Sempowski, Gregory D., Kelsoe, Garnett
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104996/
https://www.ncbi.nlm.nih.gov/pubmed/21655273
http://dx.doi.org/10.1371/journal.pone.0019957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104996/
https://www.ncbi.nlm.nih.gov/pubmed/21655273
http://dx.doi.org/10.1371/journal.pone.0019957

Ejemplares similares