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Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer

BACKGROUND: Lung cancer is the leading cause of cancer deaths worldwide, with a five-year overall survival rate of only 15%. Cancerous inhibitor of PP2A (CIP2A) is a human oncoprotein inhibiting PP2A in many human malignancies. However, whether CIP2A can be a new drug target for lung cancer is large...

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Detalles Bibliográficos
Autores principales: Ma, Liang, Wen, Zhe-Sheng, Liu, Zi, Hu, Zheng, Ma, Jun, Chen, Xiao-Qin, Liu, Yong-Qiang, Pu, Jian-Xin, Xiao, Wei-Lie, Sun, Han-Dong, Zhou, Guang-Biao
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105001/
https://www.ncbi.nlm.nih.gov/pubmed/21655278
http://dx.doi.org/10.1371/journal.pone.0020159