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Dysregulated Cytokine Expression by CD4+ T cells from Post-Septic Mice Modulates both Th1 and Th2-Mediated Granulomatous Lung Inflammation

Previous epidemiological studies in humans and experimental studies in animals indicate that survivors of severe sepsis exhibit deficiencies in the activation and effector function of immune cells. In particular, CD4+ T lymphocytes can exhibit reduced proliferative capacity and improper cytokine res...

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Detalles Bibliográficos
Autores principales: Carson, William F., Ito, Toshihiro, Schaller, Matthew, Cavassani, Karen A., Chensue, Stephen W., Kunkel, Steven L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105020/
https://www.ncbi.nlm.nih.gov/pubmed/21655295
http://dx.doi.org/10.1371/journal.pone.0020385