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Emergence and Persistence of Minor Drug-Resistant HIV-1 Variants in Ugandan Women after Nevirapine Single-Dose Prophylaxis

BACKGROUND: Nevirapine (NVP) single-dose is still a widely used antiretroviral prophylaxis for the prevention of vertical HIV-1 transmission in resource-limited settings. However, the main disadvantage of the Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) NVP is the rapid selection of NVP-re...

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Detalles Bibliográficos
Autores principales: Hauser, Andrea, Mugenyi, Kizito, Kabasinguzi, Rose, Kuecherer, Claudia, Harms, Gundel, Kunz, Andrea
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105030/
https://www.ncbi.nlm.nih.gov/pubmed/21655245
http://dx.doi.org/10.1371/journal.pone.0020357