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Colocalization of 14-3-3 Proteins with SOD1 in Lewy Body-Like Hyaline Inclusions in Familial Amyotrophic Lateral Sclerosis Cases and the Animal Model

BACKGROUND AND PURPOSE: Cu/Zn superoxide dismutase (SOD1) is a major component of Lewy body-like hyaline inclusion (LBHI) found in the postmortem tissue of SOD1-linked familial amyotrophic lateral sclerosis (FALS) patients. In our recent studies, 14-3-3 proteins have been found in the ubiquitinated...

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Detalles Bibliográficos
Autores principales: Okamoto, Yoko, Shirakashi, Yoshitomo, Ihara, Masafumi, Urushitani, Makoto, Oono, Miki, Kawamoto, Yasuhiro, Yamashita, Hirofumi, Shimohama, Shun, Kato, Shinsuke, Hirano, Asao, Tomimoto, Hidekazu, Ito, Hidefumi, Takahashi, Ryosuke
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105059/
https://www.ncbi.nlm.nih.gov/pubmed/21655264
http://dx.doi.org/10.1371/journal.pone.0020427