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Transcription Factors E2A, FOXO1 and FOXP1 Regulate Recombination Activating Gene Expression in Cancer Cells

It has long been accepted that immunoglobulins (Igs) were produced by B lymphoid cells only. Recently Igs have been found to be expressed in various human cancer cells and promote tumor growth. Recombination activating gene 1 (RAG1) and RAG2, which are essential enzymes for initiating variable-diver...

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Detalles Bibliográficos
Autores principales: Chen, Zhengshan, Xiao, Yanna, Zhang, Junjun, Li, Jing, Liu, Yuxuan, Zhao, Yingying, Ma, Changchun, Luo, Jin, Qiu, Yamei, Huang, Guowei, Korteweg, Christine, Gu, Jiang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105062/
https://www.ncbi.nlm.nih.gov/pubmed/21655267
http://dx.doi.org/10.1371/journal.pone.0020475