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Exendin-4 Improves Blood Glucose Control in Both Young and Aging Normal Non-Diabetic Mice, Possible Contribution of Beta Cell Independent Effects

AIMS: Type 2 diabetes is highly prevalent in the elderly population. Glucagon like Peptide-1 mimetic such as exendin-4 augments post-prandial insulin secretion. However, the potential influence of aging on the therapeutic effects of this peptide has not been well studied. In this study, we examined...

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Detalles Bibliográficos
Autores principales: Fan, Rongrong, Kang, Zhanfang, He, Lan, Chan, Juliana, Xu, Gang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105063/
https://www.ncbi.nlm.nih.gov/pubmed/21655268
http://dx.doi.org/10.1371/journal.pone.0020443