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Efficient Targeting of Head and Neck Squamous Cell Carcinoma by Systemic Administration of a Dual uPA and MMP-Activated Engineered Anthrax Toxin

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Although considerable progress has been made in elucidating the etiology of the disease, the prognosis for individuals diagnosed with HNSCC remains poor, underscoring the need for development of additional treat...

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Detalles Bibliográficos
Autores principales: Schafer, Jeffrey M., Peters, Diane E., Morley, Thomas, Liu, Shihui, Molinolo, Alfredo A., Leppla, Stephen H., Bugge, Thomas H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105081/
https://www.ncbi.nlm.nih.gov/pubmed/21655226
http://dx.doi.org/10.1371/journal.pone.0020532