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NAD(P)H: Quinone Oxidoreductase 1 Deficiency Conjoint with Marginal Vitamin C Deficiency Causes Cigarette Smoke Induced Myelodysplastic Syndromes

BACKGROUND: The etiology of myelodysplastic syndromes (MDS) is largely unknown. Exposure to cigarette smoke (CS) is reported to be associated with MDS risk. There is inconsistent evidence that deficiency of NAD(P)H-quinone: oxidoreductase 1 (NQO1) increases the risk of MDS. Earlier we had shown that...

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Detalles Bibliográficos
Autores principales: Das, Archita, Dey, Neekkan, Ghosh, Arunava, Das, Tanusree, Chatterjee, Indu B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105086/
https://www.ncbi.nlm.nih.gov/pubmed/21655231
http://dx.doi.org/10.1371/journal.pone.0020590