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Pirt, a TRPV1 Modulator, Is Required for Histamine-Dependent and -Independent Itch

Itch, or pruritus, is an important clinical problem whose molecular basis has yet to be understood. Recent work has begun to identify genes that contribute to detecting itch at the molecular level. Here we show that Pirt, known to play a vital part in sensing pain through modulation of the transient...

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Detalles Bibliográficos
Autores principales: Patel, Kush N., Liu, Qin, Meeker, Sonya, Undem, Bradley J., Dong, Xinzhong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105090/
https://www.ncbi.nlm.nih.gov/pubmed/21655234
http://dx.doi.org/10.1371/journal.pone.0020559