Cargando…
Pirt, a TRPV1 Modulator, Is Required for Histamine-Dependent and -Independent Itch
Itch, or pruritus, is an important clinical problem whose molecular basis has yet to be understood. Recent work has begun to identify genes that contribute to detecting itch at the molecular level. Here we show that Pirt, known to play a vital part in sensing pain through modulation of the transient...
Autores principales: | Patel, Kush N., Liu, Qin, Meeker, Sonya, Undem, Bradley J., Dong, Xinzhong |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105090/ https://www.ncbi.nlm.nih.gov/pubmed/21655234 http://dx.doi.org/10.1371/journal.pone.0020559 |
Ejemplares similares
-
TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch
por: Wilson, Sarah R., et al.
Publicado: (2011) -
Osthole inhibits histamine-dependent itch via modulating TRPV1 activity
por: Yang, Niu-Niu, et al.
Publicado: (2016) -
Pirt Together with TRPV1 Is Involved in the Regulation of Neuropathic Pain
por: Wang, Changming, et al.
Publicado: (2018) -
Riboflavin Inhibits Histamine-Dependent Itch by Modulating Transient Receptor Potential Vanilloid 1 (TRPV1)
por: Lee, Kihwan, et al.
Publicado: (2021) -
Pirt Functions as an Endogenous Regulator of TRPM8
por: Tang, Zongxiang, et al.
Publicado: (2013)