Cargando…

Biochemical Comparison of Anopheles gambiae and Human NADPH P450 Reductases Reveals Different 2′-5′-ADP and FMN Binding Traits

NADPH-cytochrome P450 oxidoreductase (CPR) plays a central role in chemical detoxification and insecticide resistance in Anopheles gambiae, the major vector for malaria. Anopheles gambiae CPR (AgCPR) was initially expressed in Eschericia coli but failed to bind 2′, 5′-ADP Sepharose. To investigate t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lian, Lu-Yun, Widdowson, Philip, McLaughlin, Lesley A., Paine, Mark J. I.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105092/ https://www.ncbi.nlm.nih.gov/pubmed/21655236 http://dx.doi.org/10.1371/journal.pone.0020574

Ejemplares similares

Allosteric modulation of cytochrome P450 enzymes by the NADPH cytochrome P450 reductase FMN-containing domain
por: Burris-Hiday, Sarah D., et al.
Publicado: (2023)

The FMN “140s Loop” of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450
por: Rwere, Freeborn, et al.
Publicado: (2021)

Genomic and Bioinformatic Analysis of NADPH-Cytochrome P450 Reductase in Anopheles stephensi (Diptera: Culicidae)
por: Suwanchaichinda, C., et al.
Publicado: (2014)

Nitroreduction of flutamide by Cunninghamella elegans NADPH: Cytochrome P450 reductase
por: Khan, Mohd Faheem, et al.
Publicado: (2022)

The Flavin-Containing Reductase Domain of Cytochrome P450 BM3 Acts as a Surrogate for Mammalian NADPH-P450 Reductase
por: Park, Seon-Ha, et al.
Publicado: (2012)

Contribution of NADPH-cytochrome P450 Reductase to Azole Resistance in Fusarium oxysporum
por: He, Dan, et al.
Publicado: (2021)

Cloning and Functional Characterization of NADPH-Cytochrome P450 Reductases in Aconitum vilmorinianum
por: Cheng, Jingping, et al.
Publicado: (2023)

Molecular Cloning and Identification of NADPH Cytochrome P450 Reductase from Panax ginseng
por: Zou, Xian, et al.
Publicado: (2021)

Field-Caught Permethrin-Resistant Anopheles gambiae Overexpress CYP6P3, a P450 That Metabolises Pyrethroids
por: Müller, Pie, et al.
Publicado: (2008)

Modeling of Anopheles minimus Mosquito NADPH-Cytochrome P450 Oxidoreductase (CYPOR) and Mutagenesis Analysis
por: Sarapusit, Songklod, et al.
Publicado: (2013)

NADPH–Cytochrome P450 Reductase Mediates the Resistance of Aphis (Toxoptera) citricidus (Kirkaldy) to Abamectin
por: Jing, Tian-Xing, et al.
Publicado: (2018)

Pyriproxyfen is metabolized by P450s associated with pyrethroid resistance in An. gambiae
por: Yunta, Cristina, et al.
Publicado: (2016)

CYP6 P450 Enzymes and ACE-1 Duplication Produce Extreme and Multiple Insecticide Resistance in the Malaria Mosquito Anopheles gambiae
por: Edi, Constant V., et al.
Publicado: (2014)

Stereospecificity of hydride transfer and molecular docking in FMN‐dependent NADH‐indigo reductase of Bacillus smithii
por: Yoneda, Kazunari, et al.
Publicado: (2021)

Silencing NADPH-cytochrome P450 reductase results in reduced acaricide resistance in Tetranychus cinnabarinus (Boisduval)
por: Shi, Li, et al.
Publicado: (2015)

Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis
por: Heintze, Tamara, et al.
Publicado: (2021)

The Interplay between Tubulins and P450 Cytochromes during Plasmodium berghei Invasion of Anopheles gambiae Midgut
por: Félix, Rute C., et al.
Publicado: (2011)

An expression map for Anopheles gambiae
por: MacCallum, Robert M, et al.
Publicado: (2011)

Tools for Anopheles gambiae Transgenesis
por: Volohonsky, Gloria, et al.
Publicado: (2015)

Phenotypic, genotypic and biochemical changes during pyrethroid resistance selection in Anopheles gambiae mosquitoes
por: Machani, Maxwell G., et al.
Publicado: (2020)

Biochemical Mechanism of Insecticide Resistance in Malaria Vector, Anopheles gambiae s.l in Nigeria
por: YUSUF, Mustapha Ahmed, et al.
Publicado: (2021)

Presence of nadph-cytochrome P-450 reductase in rat liver golgi membranes: Evidence obtained by immunoadsorption method
por: Ito, A, et al.
Publicado: (1978)

Functional characterization of NADPH-cytochrome P450 reductase from Bactrocera dorsalis: Possible involvement in susceptibility to malathion
por: Huang, Yong, et al.
Publicado: (2015)

The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength
por: Campelo, Diana, et al.
Publicado: (2017)

Sex-specific induction of CYP6 cytochrome P450 genes in cadmium and lead tolerant Anopheles gambiae
por: Musasia, Fauzia K, et al.
Publicado: (2013)

Dry season ecology of Anopheles gambiae complex mosquitoes in The Gambia
por: Jawara, Musa, et al.
Publicado: (2008)

Status of insecticide resistance in Anopheles gambiae (s.l.) of The Gambia
por: Opondo, Kevin Ochieng’, et al.
Publicado: (2019)

Crystal structures of FMN‐bound and FMN‐free forms of dihydroorotate dehydrogenase from Trypanosoma brucei
por: Kubota, Tomomi, et al.
Publicado: (2018)

Biochemical and structural insights into the cytochrome P450 reductase from Candida tropicalis
por: Ebrecht, Ana C., et al.
Publicado: (2019)

Genomic Islands of Speciation in Anopheles gambiae
por: Turner, Thomas L, et al.
Publicado: (2005)

The distribution of hatching time in Anopheles gambiae
por: Yaro, Alpha S, et al.
Publicado: (2006)

Demasculinization of the Anopheles gambiae X chromosome
por: Magnusson, Kalle, et al.
Publicado: (2012)

Ovipositional Behavior of Anopheles gambiae Mosquitoes
por: Agyapong, Jeffrey, et al.
Publicado: (2014)

Behavioral Cost & Overdominance in Anopheles gambiae
por: Diop, Malal M., et al.
Publicado: (2015)

Biochemical Characterization of Anopheles gambiae SRPN6, a Malaria Parasite Invasion Marker in Mosquitoes
por: An, Chunju, et al.
Publicado: (2012)

RNA Interference of NADPH-Cytochrome P450 Reductase Results in Reduced Insecticide Resistance in the Bed Bug, Cimex lectularius
por: Zhu, Fang, et al.
Publicado: (2012)

Correction: The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength
por: Campelo, Diana, et al.
Publicado: (2018)

Evidence of Direct Generation of Oxygen Free Radicals from Heterocyclic Amines by NADPH/Cytochrome P‐450 Reductase in vitro
por: Sato, Keizo, et al.
Publicado: (1992)

Haplotype Diversity of NADPH-Cytochrome P450 Reductase Gene of Ophiocordyceps sinensis and the Effect on Fungal Infection in Host Insects
por: Xu, Zixian, et al.
Publicado: (2020)

Comparative Analysis of NADPH-Cytochrome P450 Reductases From Legumes for Heterologous Production of Triterpenoids in Transgenic Saccharomyces cerevisiae
por: Istiandari, Pramesti, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qmcrk63d15iveeekltl5vomg8t