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Glutathione Restores the Mechanism of Synaptic Plasticity in Aged Mice to That of the Adult

Glutathione (GSH), the major endogenous antioxidant produced by cells, can modulate the activity of N-methyl-D-aspartate receptors (NMDARs) through its reducing functions. During aging, an increase in oxidative stress leads to decreased levels of GSH in the brain. Concurrently, aging is characterize...

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Detalles Bibliográficos
Autores principales: Robillard, Julie M., Gordon, Grant R., Choi, Hyun B., Christie, Brian R., MacVicar, Brian A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105108/
https://www.ncbi.nlm.nih.gov/pubmed/21655192
http://dx.doi.org/10.1371/journal.pone.0020676