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Reduced endothelial dependent vasodilation in vessels from TLR4(−/−) mice is associated with increased superoxide generation

Toll like receptor (TLR)4 is a pattern recognition receptor expressed in endothelial and other cells, responsible for the sensing of endotoxin and host derived ligands. Our group has shown previously that the absence of TLR4 is associated with reduced endothelial dependent vasodilator responses and...

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Detalles Bibliográficos
Autores principales: Harrington, Louise S., Lundberg, Martina H., Waight, Michael, Rozario, Adrian, Mitchell, Jane A.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105224/
https://www.ncbi.nlm.nih.gov/pubmed/21513697
http://dx.doi.org/10.1016/j.bbrc.2011.04.024