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Reduced endothelial dependent vasodilation in vessels from TLR4(−/−) mice is associated with increased superoxide generation
Toll like receptor (TLR)4 is a pattern recognition receptor expressed in endothelial and other cells, responsible for the sensing of endotoxin and host derived ligands. Our group has shown previously that the absence of TLR4 is associated with reduced endothelial dependent vasodilator responses and...
Autores principales: | Harrington, Louise S., Lundberg, Martina H., Waight, Michael, Rozario, Adrian, Mitchell, Jane A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105224/ https://www.ncbi.nlm.nih.gov/pubmed/21513697 http://dx.doi.org/10.1016/j.bbrc.2011.04.024 |
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