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Novel method for combined linkage and genome-wide association analysis finds evidence of distinct genetic architecture for two subtypes of autism

The Autism Genome Project has assembled two large datasets originally designed for linkage analysis and genome-wide association analysis, respectively: 1,069 multiplex families genotyped on the Affymetrix 10 K platform, and 1,129 autism trios genotyped on the Illumina 1 M platform. We set out to exp...

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Detalles Bibliográficos
Autores principales: Vieland, Veronica J., Hallmayer, Joachim, Huang, Yungui, Pagnamenta, Alistair T., Pinto, Dalila, Khan, Hameed, Monaco, Anthony P., Paterson, Andrew D., Scherer, Stephen W., Sutcliffe, James S., Szatmari, Peter
Formato: Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105232/
https://www.ncbi.nlm.nih.gov/pubmed/21484201
http://dx.doi.org/10.1007/s11689-011-9072-9