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Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

The Rho family of GTPases play important roles in morphogenesis of dendritic spines1–3 and synaptic plasticity4–9 by modulating the organization of the actin cytoskeleton10. Here, we monitored the activity of Rho GTPases, RhoA and Cdc42, in single dendritic spines undergoing structural plasticity as...

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Detalles Bibliográficos
Autores principales: Murakoshi, Hideji, Wang, Hong, Yasuda, Ryohei
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105377/
https://www.ncbi.nlm.nih.gov/pubmed/21423166
http://dx.doi.org/10.1038/nature09823