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Real-time detection of cruciform extrusion by single-molecule DNA nanomanipulation

During cruciform extrusion, a DNA inverted repeat unwinds and forms a four-way junction in which two of the branches consist of hairpin structures obtained by self-pairing of the inverted repeats. Here, we use single-molecule DNA nanomanipulation to monitor in real-time cruciform extrusion and rewin...

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Detalles Bibliográficos
Autores principales: Ramreddy, T., Sachidanandam, R., Strick, T. R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105387/
https://www.ncbi.nlm.nih.gov/pubmed/21266478
http://dx.doi.org/10.1093/nar/gkr008