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Biophysical analysis and small-angle X-ray scattering-derived structures of MeCP2–nucleosome complexes
MeCP2 is a highly abundant chromatin architectural protein with key roles in post-natal brain development in humans. Mutations in MeCP2 are associated with Rett syndrome, the main cause of mental retardation in girls. Structural information on the intrinsically disordered MeCP2 protein is restricted...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105411/ https://www.ncbi.nlm.nih.gov/pubmed/21278419 http://dx.doi.org/10.1093/nar/gkr005 |