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Biophysical analysis and small-angle X-ray scattering-derived structures of MeCP2–nucleosome complexes

MeCP2 is a highly abundant chromatin architectural protein with key roles in post-natal brain development in humans. Mutations in MeCP2 are associated with Rett syndrome, the main cause of mental retardation in girls. Structural information on the intrinsically disordered MeCP2 protein is restricted...

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Detalles Bibliográficos
Autores principales: Yang, Chenghua, van der Woerd, Mark J., Muthurajan, Uma M., Hansen, Jeffrey C., Luger, Karolin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105411/
https://www.ncbi.nlm.nih.gov/pubmed/21278419
http://dx.doi.org/10.1093/nar/gkr005