Cargando…
Biophysical analysis and small-angle X-ray scattering-derived structures of MeCP2–nucleosome complexes
MeCP2 is a highly abundant chromatin architectural protein with key roles in post-natal brain development in humans. Mutations in MeCP2 are associated with Rett syndrome, the main cause of mental retardation in girls. Structural information on the intrinsically disordered MeCP2 protein is restricted...
Autores principales: | Yang, Chenghua, van der Woerd, Mark J., Muthurajan, Uma M., Hansen, Jeffrey C., Luger, Karolin |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105411/ https://www.ncbi.nlm.nih.gov/pubmed/21278419 http://dx.doi.org/10.1093/nar/gkr005 |
Ejemplares similares
-
MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain
por: Thambirajah, Anita A., et al.
Publicado: (2012) -
Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping
por: Kernohan, Kristin D., et al.
Publicado: (2014) -
Single and double box HMGB proteins differentially destabilize nucleosomes
por: McCauley, Micah J, et al.
Publicado: (2019) -
Solution structure(s) of trinucleosomes from contrast variation SAXS
por: Mauney, Alexander W, et al.
Publicado: (2021) -
Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo
por: Connelly, John C, et al.
Publicado: (2020)