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Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre
The highly processive transcription by multi-subunit RNA polymerases (RNAP) can be interrupted by misincorporation or backtracking events that may stall transcription or lead to erroneous transcripts. Backtracked/misincorporated complexes can be resolved via hydrolysis of the transcript. Here, we sh...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105419/ https://www.ncbi.nlm.nih.gov/pubmed/21266474 http://dx.doi.org/10.1093/nar/gkq1359 |