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Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre

The highly processive transcription by multi-subunit RNA polymerases (RNAP) can be interrupted by misincorporation or backtracking events that may stall transcription or lead to erroneous transcripts. Backtracked/misincorporated complexes can be resolved via hydrolysis of the transcript. Here, we sh...

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Detalles Bibliográficos
Autores principales: Roghanian, Mohammad, Yuzenkova, Yulia, Zenkin, Nikolay
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105419/
https://www.ncbi.nlm.nih.gov/pubmed/21266474
http://dx.doi.org/10.1093/nar/gkq1359