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Clinical use of CCR5 inhibitors in HIV and beyond

Since the discovery of CCR5 as a coreceptor for HIV entry, there has been interest in blockade of the receptor for treatment and prevention of HIV infection. Although several CCR5 antagonists have been evaluated in clinical trials, only maraviroc has been approved for clinical use in the treatment o...

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Detalles Bibliográficos
Autores principales: Gilliam, Bruce L, Riedel, David J, Redfield, Robert R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105509/
https://www.ncbi.nlm.nih.gov/pubmed/21284908
http://dx.doi.org/10.1186/1479-5876-9-S1-S9