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An electrostatic potassium channel opener targeting the final voltage sensor transition

Free polyunsaturated fatty acids (PUFAs) modulate the voltage dependence of voltage-gated ion channels. As an important consequence thereof, PUFAs can suppress epileptic seizures and cardiac arrhythmia. However, molecular details for the interaction between PUFA and ion channels are not well underst...

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Detalles Bibliográficos
Autores principales: Börjesson, Sara I., Elinder, Fredrik
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105513/
https://www.ncbi.nlm.nih.gov/pubmed/21624947
http://dx.doi.org/10.1085/jgp.201110599