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Low resistance, large dimension entrance to the inner cavity of BK channels determined by changing side-chain volume

Large-conductance Ca(2+)- and voltage-activated K(+) (BK) channels have the largest conductance (250–300 pS) of all K(+)-selective channels. Yet, the contributions of the various parts of the ion conduction pathway to the conductance are not known. Here, we examine the contribution of the entrance t...

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Detalles Bibliográficos
Autores principales: Geng, Yanyan, Niu, Xiaowei, Magleby, Karl L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105516/
https://www.ncbi.nlm.nih.gov/pubmed/21576375
http://dx.doi.org/10.1085/jgp.201110616