Disconnecting the Golgi ribbon from the centrosome prevents directional cell migration and ciliogenesis

Mammalian cells exhibit a frequent pericentrosomal Golgi ribbon organization. In this paper, we show that two AKAP450 N-terminal fragments, both containing the Golgi-binding GM130-interacting domain of AKAP450, dissociated endogenous AKAP450 from the Golgi and inhibited microtubule (MT) nucleation a...

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Detalles Bibliográficos
Autores principales: Hurtado, Lidia, Caballero, Cristina, Gavilan, Maria P., Cardenas, Jesus, Bornens, Michel, Rios, Rosa M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105543/
https://www.ncbi.nlm.nih.gov/pubmed/21606206
http://dx.doi.org/10.1083/jcb.201011014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105543/
https://www.ncbi.nlm.nih.gov/pubmed/21606206
http://dx.doi.org/10.1083/jcb.201011014

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