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Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation

Splicing is a key process that expands the coding capacity of genomes. Its kinetics remain poorly characterized, and the distribution of splicing time caused by the stochasticity of single splicing events is expected to affect regulation efficiency. We conducted a small-scale survey on 40 introns in...

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Detalles Bibliográficos
Autores principales: Schmidt, Ute, Basyuk, Eugenia, Robert, Marie-Cécile, Yoshida, Minoru, Villemin, Jean-Philippe, Auboeuf, Didier, Aitken, Stuart, Bertrand, Edouard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105549/
https://www.ncbi.nlm.nih.gov/pubmed/21624952
http://dx.doi.org/10.1083/jcb.201009012