The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine

BACKGROUND: Sigma-2 receptors are over-expressed in proliferating cancer cells, making an attractive target for the targeted treatment of pancreatic cancer. In this study, we investigated the role of the novel sigma-2 receptor ligand SW43 to induce apoptosis and augment standard chemotherapy. RESULT...

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Detalles Bibliográficos
Autores principales: Hornick, John R, Xu, Jinbin, Vangveravong, Suwanna, Tu, Zhude, Mitchem, Jonathan B, Spitzer, Dirk, Goedegebuure, Peter, Mach, Robert H, Hawkins, William G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106998/
https://www.ncbi.nlm.nih.gov/pubmed/21092190
http://dx.doi.org/10.1186/1476-4598-9-298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106998/
https://www.ncbi.nlm.nih.gov/pubmed/21092190
http://dx.doi.org/10.1186/1476-4598-9-298

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