Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (SV40) large T antigen DNA-binding domain

The modular multifunctional protein large T antigen (T-ag) from simian virus 40 orchestrates many of the events needed for replication of the viral double-stranded DNA genome. This protein assembles into single and double hexamers on specific DNA sequences located at the origin of replication. This...

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Detalles Bibliográficos
Autores principales: Meinke, Gretchen, Phelan, Paul, Fradet-Turcotte, Amélie, Archambault, Jacques, Bullock, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107053/
https://www.ncbi.nlm.nih.gov/pubmed/21636896
http://dx.doi.org/10.1107/S0907444911014302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107053/
https://www.ncbi.nlm.nih.gov/pubmed/21636896
http://dx.doi.org/10.1107/S0907444911014302

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