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Distinct Functional Constraints Partition Sequence Conservation in a cis-Regulatory Element
Different functional constraints contribute to different evolutionary rates across genomes. To understand why some sequences evolve faster than others in a single cis-regulatory locus, we investigated function and evolutionary dynamics of the promoter of the Caenorhabditis elegans unc-47 gene. We fo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107193/ https://www.ncbi.nlm.nih.gov/pubmed/21655084 http://dx.doi.org/10.1371/journal.pgen.1002095 |