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Distinct Functional Constraints Partition Sequence Conservation in a cis-Regulatory Element

Different functional constraints contribute to different evolutionary rates across genomes. To understand why some sequences evolve faster than others in a single cis-regulatory locus, we investigated function and evolutionary dynamics of the promoter of the Caenorhabditis elegans unc-47 gene. We fo...

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Detalles Bibliográficos
Autores principales: Barrière, Antoine, Gordon, Kacy L., Ruvinsky, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107193/
https://www.ncbi.nlm.nih.gov/pubmed/21655084
http://dx.doi.org/10.1371/journal.pgen.1002095