Cargando…

Distinct Functional Constraints Partition Sequence Conservation in a cis-Regulatory Element

Different functional constraints contribute to different evolutionary rates across genomes. To understand why some sequences evolve faster than others in a single cis-regulatory locus, we investigated function and evolutionary dynamics of the promoter of the Caenorhabditis elegans unc-47 gene. We fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barrière, Antoine, Gordon, Kacy L., Ruvinsky, Ilya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107193/ https://www.ncbi.nlm.nih.gov/pubmed/21655084 http://dx.doi.org/10.1371/journal.pgen.1002095

Ejemplares similares

Coevolution within and between Regulatory Loci Can Preserve Promoter Function Despite Evolutionary Rate Acceleration
por: Barrière, Antoine, et al.
Publicado: (2012)

Functional Conservation of Cis-Regulatory Elements of Heat-Shock Genes over Long Evolutionary Distances
por: He, Zhengying, et al.
Publicado: (2011)

Phylum-Level Conservation of Regulatory Information in Nematodes despite Extensive Non-coding Sequence Divergence
por: Gordon, Kacy L., et al.
Publicado: (2015)

Pervasive Divergence of Transcriptional Gene Regulation in Caenorhabditis Nematodes
por: Barrière, Antoine, et al.
Publicado: (2014)

Tempo and Mode in Evolution of Transcriptional Regulation
por: Gordon, Kacy L., et al.
Publicado: (2012)

Functional Conservation of Divergent p63-Bound cis-Regulatory Elements
por: Gallardo-Fuentes, Lourdes, et al.
Publicado: (2020)

Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints
por: Irimia, Manuel, et al.
Publicado: (2012)

BLSSpeller: exhaustive comparative discovery of conserved cis-regulatory elements
por: De Witte, Dieter, et al.
Publicado: (2015)

Identification and Conservation Analysis of Cis-Regulatory Elements in Pig Liver
por: Luan, Yu, et al.
Publicado: (2019)

Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail
por: Sexton, Joel A., et al.
Publicado: (2023)

Lineage specific conservation of cis-regulatory elements in Cytokinin Response Factors
por: Powell, Rachel V., et al.
Publicado: (2019)

OrthReg: a tool to predict cis-regulatory elements based on cross-species orthologous sequence conservation
por: Ma, Yun-Fei, et al.
Publicado: (2020)

Identification of clade-wide putative cis-regulatory elements from conserved non-coding sequences in Cucurbitaceae genomes
por: Song, Hongtao, et al.
Publicado: (2023)

Profiling of conserved non-coding elements upstream of SHOX and functional characterisation of the SHOX cis-regulatory landscape
por: Verdin, Hannah, et al.
Publicado: (2015)

Identification and characterization of conserved noncoding cis-regulatory elements that impact Mecp2 expression and neurological functions
por: Shao, Yingyao, et al.
Publicado: (2021)

Pairs of Adjacent Conserved Noncoding Elements Separated by Conserved Genomic Distances Act as Cis-Regulatory Units
por: Li, Lifei, et al.
Publicado: (2018)

Identification of an Evolutionarily Conserved Cis-Regulatory Element Controlling the Peg3 Imprinted Domain
por: Thiaville, Michelle M., et al.
Publicado: (2013)

Cis-regulatory elements in conserved non-coding sequences of nuclear receptor genes indicate for crosstalk between endocrine systems
por: Cruz, Maria Araceli Diaz, et al.
Publicado: (2021)

Studying the functional conservation of cis-regulatory modules and their transcriptional output
por: Bauer, Denis C, et al.
Publicado: (2008)

Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements
por: Erceg, Jelena, et al.
Publicado: (2017)

Functional validation of transposable element–derived cis-regulatory elements in Atlantic salmon
por: Sahlström, Hanna M, et al.
Publicado: (2023)

Modeling an Evolutionary Conserved Circadian Cis-Element
por: Paquet, Eric R, et al.
Publicado: (2008)

Cis-regulatory Landscape Size, Constraint, and Tissue Specificity Associate with Gene Function and Expression
por: Benton, Mary Lauren, et al.
Publicado: (2023)

Recurrent Modification of a Conserved Cis-Regulatory Element Underlies Fruit Fly Pigmentation Diversity
por: Rogers, William A., et al.
Publicado: (2013)

Ancestrally Duplicated Conserved Noncoding Element Suggests Dual Regulatory Roles of HOTAIR in cis and trans
por: Nepal, Chirag, et al.
Publicado: (2020)

Role of CNSs Conserved Distal Cis-Regulatory Elements in CD4 + T Cell Development and Differentiation
por: Long, Xunyi, et al.
Publicado: (2022)

A cis-regulatory module activating transcription in the suspensor contains five cis-regulatory elements
por: Henry, Kelli F., et al.
Publicado: (2015)

Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants
por: Lee, Dongwon, et al.
Publicado: (2018)

Caenorhabditis elegans cisRED: a catalogue of conserved genomic elements
por: Sleumer, Monica C., et al.
Publicado: (2009)

CEAS: cis-regulatory element annotation system
por: Ji, Xuwo, et al.
Publicado: (2006)

Redundancy and the Evolution of Cis-Regulatory Element Multiplicity
por: Paixão, Tiago, et al.
Publicado: (2010)

Epistatic Interactions in the Arabinose Cis-Regulatory Element
por: Lagator, Mato, et al.
Publicado: (2016)

Systematic identification of functional modules and cis-regulatory elements in Arabidopsis thaliana
por: Ruan, Jianhua, et al.
Publicado: (2011)

Genes associated with the cis-regulatory functions of intragenic LINE-1 elements
por: Wanichnopparat, Wachiraporn, et al.
Publicado: (2013)

Pneumococcal capsule expression is controlled through a conserved, distal cis-regulatory element during infection
por: Glanville, David G., et al.
Publicado: (2023)

PlantPAN: Plant promoter analysis navigator, for identifying combinatorial cis-regulatory elements with distance constraint in plant gene groups
por: Chang, Wen-Chi, et al.
Publicado: (2008)

Distinct Cis Regulatory Elements Govern the Expression of TAG1 in Embryonic Sensory Ganglia and Spinal Cord
por: Hadas, Yoav, et al.
Publicado: (2013)

Conservation and Evolution of Cis-Regulatory Systems in Ascomycete Fungi
por: Gasch, Audrey P, et al.
Publicado: (2004)

Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans
por: Hansen, Tyler, et al.
Publicado: (2023)

Transposable elements as a potent source of diverse cis-regulatory sequences in mammalian genomes
por: Sundaram, Vasavi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_th4tskhfuuouo8r8v7n0k643cs