Genomic Prevalence of Heterochromatic H3K9me2 and Transcription Do Not Discriminate Pluripotent from Terminally Differentiated Cells

Cellular differentiation entails reprogramming of the transcriptome from a pluripotent to a unipotent fate. This process was suggested to coincide with a global increase of repressive heterochromatin, which results in a reduction of transcriptional plasticity and potential. Here we report the dynami...

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Detalles Bibliográficos
Autores principales: Lienert, Florian, Mohn, Fabio, Tiwari, Vijay K., Baubec, Tuncay, Roloff, Tim C., Gaidatzis, Dimos, Stadler, Michael B., Schübeler, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107198/
https://www.ncbi.nlm.nih.gov/pubmed/21655081
http://dx.doi.org/10.1371/journal.pgen.1002090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107198/
https://www.ncbi.nlm.nih.gov/pubmed/21655081
http://dx.doi.org/10.1371/journal.pgen.1002090

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