Mammalian BTBD12 (SLX4) Protects against Genomic Instability during Mammalian Spermatogenesis

The mammalian ortholog of yeast Slx4, BTBD12, is an ATM substrate that functions as a scaffold for various DNA repair activities. Mutations of human BTBD12 have been reported in a new sub-type of Fanconi anemia patients. Recent studies have implicated the fly and worm orthologs, MUS312 and HIM-18, i...

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Detalles Bibliográficos
Autores principales: Holloway, J. Kim, Mohan, Swapna, Balmus, Gabriel, Sun, Xianfei, Modzelewski, Andrew, Borst, Peter L., Freire, Raimundo, Weiss, Robert S., Cohen, Paula E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107204/
https://www.ncbi.nlm.nih.gov/pubmed/21655083
http://dx.doi.org/10.1371/journal.pgen.1002094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107204/
https://www.ncbi.nlm.nih.gov/pubmed/21655083
http://dx.doi.org/10.1371/journal.pgen.1002094

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