Integrative DNA Methylation and Gene Expression Analyses Identify DNA Packaging and Epigenetic Regulatory Genes Associated with Low Motility Sperm

BACKGROUND: In previous studies using candidate gene approaches, low sperm count (oligospermia) has been associated with altered sperm mRNA content and DNA methylation in both imprinted and non-imprinted genes. We performed a genome-wide analysis of sperm DNA methylation and mRNA content to test for...

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Detalles Bibliográficos
Autores principales: Pacheco, Sara E., Houseman, E. Andres, Christensen, Brock C., Marsit, Carmen J., Kelsey, Karl T., Sigman, Mark, Boekelheide, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107223/
https://www.ncbi.nlm.nih.gov/pubmed/21674046
http://dx.doi.org/10.1371/journal.pone.0020280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107223/
https://www.ncbi.nlm.nih.gov/pubmed/21674046
http://dx.doi.org/10.1371/journal.pone.0020280

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