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Transmigration of Melanoma Cells through the Blood-Brain Barrier: Role of Endothelial Tight Junctions and Melanoma-Released Serine Proteases

Malignant melanoma represents the third common cause of brain metastasis, having the highest propensity to metastasize to the brain of all primary neoplasms in adults. Since the central nervous system lacks a lymphatic system, the only possibility for melanoma cells to reach the brain is via the blo...

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Detalles Bibliográficos
Autores principales: Fazakas, Csilla, Wilhelm, Imola, Nagyőszi, Péter, Farkas, Attila E., Haskó, János, Molnár, Judit, Bauer, Hannelore, Bauer, Hans-Christian, Ayaydin, Ferhan, Dung, Ngo Thi Khue, Siklós, László, Krizbai, István A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107231/
https://www.ncbi.nlm.nih.gov/pubmed/21674054
http://dx.doi.org/10.1371/journal.pone.0020758