Targeting SET/I(2)PP2A Oncoprotein Functions as a Multi-pathway Strategy for Cancer Therapy

The SET oncoprotein participates in cancer progression by affecting multiple cellular processes, inhibiting the tumor suppressor PP2A and inhibiting the metastasis suppressor nm23-H1. Based upon these multiple activities, we hypothesized that targeted inhibition of SET would have multiple discrete a...

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Detalles Bibliográficos
Autores principales: Switzer, Christopher H., Cheng, Robert Y.S., Vitek, Timothy M., Christensen, Dale J., Wink, David A., Vitek, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107340/
https://www.ncbi.nlm.nih.gov/pubmed/21297667
http://dx.doi.org/10.1038/onc.2010.622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107340/
https://www.ncbi.nlm.nih.gov/pubmed/21297667
http://dx.doi.org/10.1038/onc.2010.622

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