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Subcellular Spatial Regulation of Canonical Wnt Signaling at the Primary Cilium

Mechanisms of signal transduction regulation remain a fundamental question in a variety of biological processes and diseases. Previous evidence suggests the primary cilium can act as a signaling hub(1), but its exact role in many of its described pathways has remained elusive. Here, we investigate t...

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Detalles Bibliográficos
Autores principales: Lancaster, Madeline A., Schroth, Jana, Gleeson, Joseph G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107376/
https://www.ncbi.nlm.nih.gov/pubmed/21602792
http://dx.doi.org/10.1038/ncb2259