The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

How individual cells respond to mechanical forces is of considerable interest to biologists as force affects many aspects of cell behavior(1). Application of force on integrins triggers cytoskeletal rearrangements and growth of the associated adhesion complex, resulting in increased cellular stiffne...

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Detalles Bibliográficos
Autores principales: Guilluy, Christophe, Swaminathan, Vinay, Garcia-Mata, Rafael, O’Brien, E. Timothy, Superfine, Richard, Burridge, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107386/
https://www.ncbi.nlm.nih.gov/pubmed/21572419
http://dx.doi.org/10.1038/ncb2254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107386/
https://www.ncbi.nlm.nih.gov/pubmed/21572419
http://dx.doi.org/10.1038/ncb2254

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