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The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins
How individual cells respond to mechanical forces is of considerable interest to biologists as force affects many aspects of cell behavior(1). Application of force on integrins triggers cytoskeletal rearrangements and growth of the associated adhesion complex, resulting in increased cellular stiffne...
Autores principales: | Guilluy, Christophe, Swaminathan, Vinay, Garcia-Mata, Rafael, O’Brien, E. Timothy, Superfine, Richard, Burridge, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107386/ https://www.ncbi.nlm.nih.gov/pubmed/21572419 http://dx.doi.org/10.1038/ncb2254 |
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