Identification and Characterization of a Loss-of-Function Human MPYS Variant

MPYS, also known as STING and MITA, is an IFNβ stimulator essential for host defense against RNA, DNA viruses and intracellular bacteria. MPYS also facilitates the adjuvant activity of DNA vaccines. Here we report identification of a distinct human MPYS haplotype that contains three non-synonymous S...

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Detalles Bibliográficos
Autores principales: Jin, Lei, Xu, Liang-guo, Yang, Ivana V., Davidson, Elizabeth J., Schwartz, David A., Wurfel, Mark M., Cambier, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107388/
https://www.ncbi.nlm.nih.gov/pubmed/21248775
http://dx.doi.org/10.1038/gene.2010.75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107388/
https://www.ncbi.nlm.nih.gov/pubmed/21248775
http://dx.doi.org/10.1038/gene.2010.75

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